Already mentioned at the end of the thirteenth century in the list of Liber Notitiae Sanctorum Mediolani by Goffredo da Bussero, in which it is stated that in Muggiasca there were only three churches, San Lorenzo in Vendrogno assumed the title of parish church in 1368, when it was detached from the provostry of Bellano. It then went under the jurisdiction of the parish of Primaluna, religious capital of Valsassina, and then returned to depend on Bellano following the establishment of the recently constituted pastoral unit.